Na Transport across Frog Skin at Low External Na Concentrations
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چکیده
منابع مشابه
Na Transport across Frog Skin at Low External Na Concentrations
T h e ac t ive t r a n s p o r t of N a across i sola ted f r o g skin h a s b e e n e x a m i n e d extensively, b u t in t h e m a j o r i t y of s tudies t h e o u t e r sur face of t h e skin h a s b e e n b a t h e d w i t h solut ions c o n t a i n i n g re la t ive ly h i g h (115 mM) c o n c e n t r a t i o n s of N a . V a r i a t i o n in ra tes of N a t r a n s p o r t a n d in elect...
متن کاملThe Influence of Na Concentration on Na Transport across Frog Skin
The effects of changes in Na concentration of the bathing solutions on some transport and permeability properties of the isolated frog skin have been examined. Rate coefficients for unidirectional Na movements across the two major barriers in the skin have been estimated as functions of Na concentration. The results indicate that the "apparent Na permeability" of the outer barrier of the skin d...
متن کاملThe Effect of Ca and Antidiuretic Hormone on Na Transport across Frog Skin
A method has been developed for determining unidirectional Na fluxes across the two faces of the transporting cells in the frog skin. The method has been used to investigate the location of the sites at which Ca and anti-diuretic hormone act to alter the rate of active Na transport across the skin. The results have indicated that the primary effect of both agents is on the Na permeability of th...
متن کاملTransepithelial sodium transport across frog skin.
AMPHIBIAN SKIN SERVES as an extra renal organ for the regulation of ion transport across the epithelium (2). Ion channels and transporters present in the epithelium of frog skin assist in the regulation of the same. These channels and transporters are necessary for the maintenance of intracellular ionic concentrations, osmotic concentration and cell integrity, and function (4). Figure 1A depict...
متن کاملLocalization of Na+-pump sites in frog skin
The localization of Na+-pump sites (Na+-K+-ATPase) in the frog skin epithelium was determined by a freeze-dry radioautographic method for identifying [3H]ouabain-binding sites. Ventral pelvic skins of Rana catesbeiana were mounted in Ussing chambers and exposed to 10(-6) M [3H]ouabain for 120 min, washed in ouabain-free Ringer's solution for 60 min, and then processed for radioautography. Ouaba...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1966
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.0491161